Hypermobile Elhers-Danlos syndrome at its core is a connective tissue condition characterised by joint hypermobility, joint instability and chronic pain. This condition affects collagen and other components of the extracellular matrix proteins, which are essential for providing strength and flexibility to the skin, joints, and blood vessels.
But hEDS is far more complex than simply being overly flexible. It presents with a wide range of systemic symptoms that can significantly impact daily life and vary considerably between individuals. As such, a holistic, multidisciplinary approach to management is essential.
Core features:
· Joint Hypermobility
· Joint Instability
· Chronic Pain
· Mild Skin hyperextensibility
· Abnormal scarring
Other associated symptoms:
· Gastrointestinal issues
· Headaches
· Chronic Fatigue
· Mast cell activation diseases
Causes:
There is no current research identifying a cause for hEDS, however it is evident that hEDS is hereditary with there being a 50% chance of passing the condition onto children.
Diagnosis:
If these symptoms sound very familiar it is worth a while following up with a Rheumatologist or GP to get diagnosed. There is no genetic marker for diagnosis however there is a 2017 clinical criteria that is often utilised. It may end up being a huge eye-opener allowing you to connect the dots between different health issues you may have been facing.
How physiotherapy can help?
· Improving Joint stability
· Targeted and tailored Exercise plans will assist in strengthening the appropriate muscles that will gradually increase joint stability.
· Reduce Pain
· Adjusting poor movement mechanics that may be linked to the pain.
· Strengthening muscles so they can handle load without pain
· Managing fatigue
· Using pacing strategies and gentle, graded exercise to improve endurance without overloading the system.
Final thoughts:
A holistic approach is essential for the effective management of Hypermobile Ehlers-Danlos Syndrome (hEDS). Since symptoms can vary widely from person to person, it’s important to seek professional guidance and develop a personalised treatment plan tailored to your specific needs. With the right support, you can better manage your symptoms and work toward improving your overall quality of life.
The Ehlers-Danlos Society. (2025). Hypermobile Ehlers-Danlos Syndrome (hEDS). Retrieved from https://www.ehlers-danlos.com/heds/
Hypermobility Health. (2025). The EDS Iceberg: Understanding the Invisible Burden of Ehlers-Danlos Syndrome. Retrieved from https://hypermobilityhealth.com.au/wp-content/uploads/2025/01/EDS-iceberg-iStock-1401249912-1536x864.jpg